A pharmaceutical/chemical process like a crystallization, dispersion, vial filling etc. needs to be developed. It is sensitive to mixing and it is required to design a well-understood, robust process.
We setup Computational Fluid Dynamics (CFD) simulations for all involved vessel/reactor configurations at Lab-Scale and perform a general sensitivity analysis on the operating conditions to derive CFD-based DoE’s. The gained understanding allows to select suitable industrial scale equipment.
Typical initial situation
A pharmaceutical/chemical process like a crystallization needs to be transferred from one production site to another. Due to changes in equipment there is a risk of failure that needs to be avoided.
We setup Computational Fluid Dynamics (CFD) simulations for both, the current and the future vessel/reactor configuration and tune the operating conditions of the future setup to match the process critical parameters.